To support architectural changes, the upcoming DataMiner 10.1.11 feature release will require .NET Framework 4.8. For the DataMiner 10.1.12 feature release, .NET 5.0 will be required as well.
These will be included in the DataMiner upgrade packages, so you don’t necessarily have to go chase down the correct .NET version yourself.
However, note that updating the .NET version requires a server reboot. This means that, unless you already have the required .NET version installed, the upgrade to DataMiner 10.1.11 and 10.1.12 will require a reboot. Keep this in mind when you plan the upgrade!