This is possible to do.
The main thing to keep in mind configuration wise is to ensure that each DMS has its own bespoke keyspace/database prefix configured in the configuration in DB.xml
As each prefix is used to uniquely identify the data which belongs to a specific DMS.
Once multiple systems are connected, it is useful to be mindful of the resource usage on the clustered databases. Therefore we would recommend making use of the cluster monitors for Cassandra and Elastic/Opensearch to monitor the clustered databases.
With Kind Regards,