The Skyline DataMiner folder itself needs to be present under the C drive.

However, I'm wondering if it isn't possible to work with a junction. According to the documentation of Microsoft Hard Links and Junctions , a junction can link directories located on different local volumes on the same computer.

This way the C:\Skyline DataMiner folder would be the junction, while the real data is located on a folder in a different local drive.

Something like below, but then the source of the junction is on a different local drive:

***DISCLAIMER***
This is just an idea that has not been tested. Please do not try this on a production setup.